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DNA Build
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Educational Use
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Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Janet Yowell
Malinda Schaefer Zarske
Megan Schroeder
Date Added:
09/18/2014
DNA Forensics and Color Pigments
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Educational Use
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Students perform DNA forensics using food coloring to enhance their understanding of DNA fingerprinting, restriction enzymes, genotyping and DNA gel electrophoresis. They place small drops of different food coloring ("water-based paint") on strips of filter paper and then place one paper strip end in water. As water travels along the paper strips, students observe the pigments that compose the paint decompose into their color components. This is an example of the chromatography concept applied to DNA forensics, with the pigments in the paint that define the color being analogous to DNA fragments of different lengths.

Subject:
Applied Science
Engineering
Genetics
Life Science
Physical Science
Physics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
DNA: The Human Body Recipe
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Educational Use
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As a class, students work through an example showing how DNA provides the "recipe" for making our body proteins. They see how the pattern of nucleotide bases (adenine, thymine, guanine, cytosine) forms the double helix ladder shape of DNA, and serves as the code for the steps required to make genes. They also learn some ways that engineers and scientists are applying their understanding of DNA in our world.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Activity/Lab
Lesson Plan
Teaching/Learning Strategy
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Frank Burkholder
Jessica Todd
Malinda Schaefer Zarske
Date Added:
09/18/2014
Discovering Genes Associated with Diseases and Traits in Dogs
Conditional Remix & Share Permitted
CC BY-NC-SA
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In this video module, students learn how scientists use genetic information from dogs to find out which gene (out of all 20,000 dog genes) is associated with any specific trait or disease of interest. This method involves comparing hundreds of dogs with the trait to hundreds of dogs not displaying the trait, and examining which position on the dog DNA is correlated with the trait (i.e. has one DNA sequence in dogs with the trait but another DNA sequence in dogs not displaying the trait). Students will also learn something about the history of dog breeds and how this history helps us find genes.

Subject:
Biology
Genetics
Life Science
Zoology
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Elinor Karlsson
Date Added:
06/15/2021
Don't Be a Square
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Educational Use
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After watching video clips from the Harry Potter and the Goblet of Fire movie, students explore the use of Punnett squares to predict genetic trait inheritance. The objective of this lesson is to articulate concepts related to genetics through direct immersive interaction based on the theme, The Science Behind Harry Potter. Students' interest is piqued by the use of popular culture in the classroom.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christine Hawthorne
Rachel Howser
Date Added:
09/18/2014
Engineering Nature: DNA Visualization and Manipulation
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Educational Use
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Students are introduced to genetic techniques such as DNA electrophoresis and imaging technologies used for molecular and DNA structure visualization. In the field of molecular biology and genetics, biomedical engineering plays an increasing role in the development of new medical treatments and discoveries. Engineering applications of nanotechnology such as lab-on-a-chip and deoxyribonucleic acid (DNA) microarrays are used to study the human genome and decode the complex interactions involved in genetic processes.

Subject:
Applied Science
Engineering
Genetics
Life Science
Physical Science
Physics
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
Engineering Out of Harry Situations: The Science Behind Harry Potter
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Educational Use
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Under the "The Science Behind Harry Potter" theme, a succession of diverse complex scientific topics are presented to students through direct immersive interaction. Student interest is piqued by the incorporation of popular culture into the classroom via a series of interactive, hands-on Harry Potter/movie-themed lessons and activities. They learn about the basics of acid/base chemistry (invisible ink), genetics and trait prediction (parseltongue trait in families), and force and projectile motion (motion of the thrown remembrall). In each lesson and activity, students are also made aware of the engineering connections to these fields of scientific study.

Subject:
Applied Science
Chemistry
Engineering
Genetics
Life Science
Mathematics
Physical Science
Physics
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christine Hawthorne
Rachel Howser
Date Added:
09/18/2014
Evolving TCE Biodegraders
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Educational Use
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A hypothetical scenario is introduced in which the class is asked to apply their understanding of the forces that drive natural selection to prepare a proposal along with an environmental consulting company to help clean up an area near their school that is contaminated with trichloroethylene (TCE). Students use the Avida-ED software application to test hypotheses for evolving (engineering) a strain of bacteria that can biodegrade TCE, resulting in a non-hazardous clean-up solution. Conduct this design challenge activity after completion of the introduction to digital evolution activity, Studying Evolution with Digital Organisms.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Amy Lark
Louise Mead
Robert Pennock
Wendy Johnson
Date Added:
09/18/2014
Gene Expression - The Basics
Unrestricted Use
CC BY
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Express yourself through your genes! See if you can generate and collect three types of protein, then move on to explore the factors that affect protein synthesis in a cell.

Subject:
Genetics
Life Science
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Ariel Paul
George Emanuel
John Blanco
Kathy Perkins
Mike Klymkowsky
Tom Perkins
Date Added:
08/20/2012
Gene Machine: The Lac Operon
Unrestricted Use
CC BY
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Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Subject:
Genetics
Life Science
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
George Spiegelman
Jared Taylor
John Blanco
Kathy Perkins
Noah Podolefsky
Date Added:
05/01/2010
Gene Machine: The Lac Operon (AR)
Unrestricted Use
CC BY
Rating
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Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Subject:
Genetics
Life Science
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
George Speigelman
Jared Taylor
John Blanco
Kathy Perkins
Noah Podolefsky
Date Added:
05/01/2010
The Genetic Basis of Inheritance and Variation
Conditional Remix & Share Permitted
CC BY-NC-SA
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The topic of this video module is genetic basis for variation among humans. The main learning objective is that students will learn the genetic mechanisms that cause variation among humans (parents and children, brothers and sisters) and how to calculate the probability that two individuals will have an identical genetic makeup. This module does not require many prerequisites, only a general knowledge of DNA as the genetic material, as well as a knowledge of meiosis.

Subject:
Biology
Genetics
Life Science
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Amjad Mahasneh
Date Added:
06/15/2021
Geneticist Pardis Sabeti
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Educational Use
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In this video profile adapted from NOVA scienceNOW, learn about geneticist and rock musician Pardis Sabeti, whose innovative insights into natural selection demonstrated how beneficial mutations spread quickly through a population.

Subject:
Genetics
Life Science
Material Type:
Lecture
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Author:
Alfred P. Sloan Foundation
HHMI
National Science Foundation
Public Television Viewers
WGBH Educational Foundation
Date Added:
08/20/2008
Heredity Mix n Match
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Educational Use
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Students randomly select jelly beans (or other candy) that represent genes for several human traits such as tongue-rolling ability and eye color. Then, working in pairs (preferably of mixed gender), students randomly choose new pairs of jelly beans from those corresponding to their own genotypes. The new pairs are placed on toothpicks to represent the chromosomes of the couple's offspring. Finally, students compare genotypes and phenotypes of parents and offspring for all the "couples" in the class. In particular, they look to see if there are cases where parents and offspring share the exact same genotype and/or phenotype, and consider how the results would differ if they repeated the simulation using more than four traits.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mary R. Hebrank
Date Added:
09/26/2008
Human Biology - Genetics (Student's Edition)
Conditional Remix & Share Permitted
CC BY-NC-SA
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The Genetics Student Edition book is one of ten volumes making up the Human Biology curriculum, an interdisciplinary and inquiry-based approach to the study of life science.

Subject:
Biology
Genetics
Life Science
Material Type:
Activity/Lab
Textbook
Provider:
CK-12 Foundation
Provider Set:
CK-12 FlexBook
Author:
Program in Human Biology, Stanford University
Date Added:
02/04/2011
Human Chromosome 2
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Educational Use
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In this video segment adapted from NOVA: Judgment Day: Intelligent Design on Trial, learn how modern genetics and molecular biology offer compelling support for evolution. The video features an interview with biologist Ken Miller.

Subject:
Anthropology
Genetics
Life Science
Social Science
Material Type:
Lecture
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Author:
Vulcan Productions, Inc.
WGBH Educational Foundation
Date Added:
11/01/2007