The goal of this lesson is to introduce students who are interested in human biology and biochemistry to the subtleties of energy metabolism (typically not presented in standard biology and biochemistry textbooks) through the lens of ATP as the primary energy currency of the cell. Avoiding the details of the major pathways of energy production (such as glycolysis, the citric acid cycle, and oxidative phosphorylation), this lesson is focused exclusively on ATP, which is truly the fuel of life. Starting with the discovery and history of ATP, this lesson will walk the students through 8 segments (outlined below) interspersed by 7 in-class challenge questions and activities, to the final step of ATP production by the ATP synthase, an amazing molecular machine. A basic understanding of the components and subcellular organization (e.g. organelles, membranes, etc.) and chemical foundation (e.g. biomolecules, chemical equilibrium, biochemical energetics, etc.) of a eukaryotic cell is a desired prerequisite, but it is not a must. Through interactive in-class activities, this lesson is designed to spark the students’ interest in biochemistry and human biology as a whole, but could serve as an introductory lesson to teaching advanced concepts of metabolism and bioenergetics in high school depending on the local science curriculum. No supplies or materials are needed.

Reviews selected issues including learning, cognition, perception, foraging and feeding, migration and navigation, defense, and social activities including conflict, collaboration, courtship and reproduction, and communication. The interacting contributions of environment and heredity are examined and the approaches of psychology, ethology, and ecology to this area of study are treated. The relation of human behavior patterns to those of nonhuman animals is explored. Additional readings and a paper are required for graduate credit.

Systematic development of reading, writing, and oral communication skills. Introduction to advanced grammar that deepens the understanding of Japanese culture and society through reading and discussion. Lab work required. This course covers lessons 22 through 27 of Japanese: The Spoken Language by Eleanor H. Jordan with Mari Noda. The goal of the course is to continue to build oral proficiency by expanding your knowledge of vocabulary and grammar. Class hours will be devoted to developing speaking skills in a variety of circumstances; making requests, invitations, apologies, suggestions, dealing with problems, expressing your opinions, etc. Grammatical and social appropriateness on your utterances will be stressed. Keep in mind that daily tape-work is essential.

Continuation of 21F.505. Further development of reading, writing, and oral communication skills. Extension of advanced grammar and further enhancement of advanced vocabulary. Variety of cultural elements studied through readings, video, and discussion. Lab work required. This course covers Lessons 27 through 30 of Japanese: The Spoken Language by Eleanor H. Jordan with Mari Noda. The goal of the course is to continue expanding grammar and vocabulary by further developing four skills: speaking, listening, reading, and writing. The goal is to acquire the ability to use Japanese appropriately with increasing spontaneity emphasized, and to be prepared to become an independent learner to the point where you are capable of handling authentic Japanese by yourself, without fear or hesitation.

Advanced subject focusing on techniques, format, and prose style used in academic and professional life. Emphasis on writing as required in fields such as economics, political science, and architecture. Short assignments include: business letters, memos, and proposals that lead toward a written term project. Methods designed to deal with the special problems of those whose first language is not English. Successful completion satisfies Phase II of the Writing Requirement. This workshop is designed to help you write clearly, accurately and effectively in both an academic and a professional environment. In class, we analyze various forms of writing and address problems common to advanced speakers of English. We will often read one another's work.

Examines in detail the works of several American authors. Through close readings of poetry, novels, or plays, subject addresses such issues as literary influence, cultural diversity, and the writer's career. Topic: American Women Authors. This subject, crosslisted in Literature and Women's Studies, examines a range of American women authors from the seventeenth century to the present. It aims to introduce a number of literary genres and styles- the captivity narrative, slave novel, sensational, sentimental, realistic, and postmodern fiction- and also to address significant historical events in American women's history: Puritanism, the American Revolution, industrialization and urbanization in the nineteenth century, the Harlem Renaissance, World War II, the 60s civil rights movements. A primary focus will be themes studied and understood through the lens of gender: war, violence, and sexual exploitation (Keller, Rowlandson, Rowson); the relationship between women and religion (Rowlandson, Rowson, Stowe); labor, poverty, and working conditions for women (Fern, Davis, Wharton); captivity and slavery (Rowlandson, Jacobs); class struggle (Fern, Davis, Wharton, Larsen); race and identity (Keller, Jacobs, Larsen, Morrison); feminist revisions of history (Stowe, Morrison, Keller); and the myth of the fallen woman (take your pick). Essays and inclass reports will focus more particularly on specific writers and themes and will stress the skills of close reading, annotation, research, and uses of multimedia where appropriate. A classroom electronic archive has been developed for this course and will be available as a resource for images and other media materials.

This class analyzes complex biological processes from the molecular, cellular, extracellular, and organ levels of hierarchy. Emphasis is placed on the basic biochemical and biophysical principles that govern these processes. Examples of processes to be studied include chemotaxis, the fixation of nitrogen into organic biological molecules, growth factor and hormone mediated signaling cascades, and signaling cascades leading to cell death in response to DNA damage. In each case, the availability of a resource, or the presence of a stimulus, results in some biochemical pathways being turned on while others are turned off. The course examines the dynamic aspects of these processes and details how biochemical mechanistic themes impinge on molecular/cellular/tissue/organ-level functions. Chemical and quantitative views of the interplay of multiple pathways as biological networks are emphasized. Student work will culminate in the preparation of a unique grant application in an area of biological networks.

This course will acquaint the student with some of the ancient Greek contributions to the Western philosophical and scientific tradition. We will examine a broad range of central philosophical themes concerning: nature, law, justice, knowledge, virtue, happiness, and death. There will be a strong emphasis on analyses of arguments found in the texts.

History of Ancient Greece from the Bronze Age to the death of Alexander. Major social, economic, political, and religious trends. Homer, heroism, and the Greek identity; the hoplite revolution and the rise of the city-state; Herodotus, Persia, and the (re)birth of history; Empire, Thucydidean rationalism, and the Peloponnesian War; Platonic constructs; Aristotle, Macedonia, and Hellenism. Emphasis on use of primary sources in translation.

This course covers the history of Rome from its humble beginnings to the 5th century A.D. The first half covers Kingship to Republican form; the conquest of Italy; Roman expansion: Pyrrhus, Punic Wars and provinces; classes, courts, and the Roman revolution; Augustus and the formation of empire. The second half covers Virgil to the Vandals; major social, economic, political and religious trends at Rome and in the provinces. There is an emphasis on the use of primary sources in translation.

This class examines the ways humans experience the realm of sound and how perceptions and technologies of sound emerge from cultural, economic, and historical worlds. In addition to learning about how environmental, linguistic, and musical sounds are construed cross-culturally, students learn about the rise of telephony, architectural acoustics, and sound recording, as well as about the globalized travel of these technologies. Questions of ownership, property, authorship, and copyright in the age of digital file sharing are also addressed. A major concern will be with how the sound/noise boundary has been imagined, created, and modeled across diverse sociocultural and scientific contexts. Auditory examples--sound art, environmental recordings, music--will be provided and invited throughout the term.

The purpose of this video lesson is to expand the student's knowledge about enzymes by introducing the antioxidant enzymes that are intimately involved in the prevention of cellular damage and eventual slowing of the aging process and prevention of several diseases. Students will learn that natural antioxidant enzymes are manufactured in the body and provide an important defense against free radicals. The topic of free radical action is introduced, covering how they are constantly generated in living cells both by ''accidents of chemistry'' and also by specific metabolic processes.

The main objective of this lesson is to illustrate an important application of mathematics in practical life -- namely in art. Most of the pictures selected for this lesson are visible on the walls of Al-Hambra – Granada (Spain), which is one of the most important landmarks in the Islamic civilization. There are three educational goals for this lesson: (1) establishing the concept of isometries; (2) giving real-life examples of groups; (3) demonstrating the importance of matrices and their applications. As background for this lesson, students just need some familiarity with the concept of a group and a limited knowledge about matrices and the inverse of a non-singular matrix.

This learning video deals with a question of geometrical probability. A key idea presented is the fact that a linear equation in three dimensions produces a plane. The video focuses on random triangles that are defined by their three respective angles. These angles are chosen randomly subject to a constraint that they must sum to 180 degrees. An example of the types of in-class activities for between segments of the video is: Ask six students for numbers and make those numbers the coordinates x,y of three points. Then have the class try to figure out how to decide if the triangle with those corners is acute or obtuse.

A writing practicum associated with 11.200 and 11.205 that focuses on helping students present their ideas in cogent, persuasive arguments and other analytical frameworks. Reading and writing assignments and other exercises stress the connections between clear thinking, critical reading, and effective writing.

The purpose of this learning video is to show students how to think more freely about math and science problems. Sometimes getting an approximate answer in a much shorter period of time is well worth the time saved. This video explores techniques for making quick, back-of-the-envelope approximations that are not only surprisingly accurate, but are also illuminating for building intuition in understanding science. This video touches upon 10th-grade level Algebra I and first-year high school physics, but the concepts covered (velocity, distance, mass, etc) are basic enough that science-oriented younger students would understand. If desired, teachers may bring in pendula of various lengths, weights to hang, and a stopwatch to measure period. Examples of in- class exercises for between the video segments include: asking students to estimate 29 x 31 without a calculator or paper and pencil; and asking students how close they can get to a black hole without getting sucked in.

The aim of this video is to introduce high school students to the engineering concept of road construction and to the reasons why problems might arise in road construction. Presentation of this concept is made more accessible to students by comparing road construction to the art of baking a layer cake. This simple comparison can serve to emphasize how important it is to follow proper procedures and to use proper materials for successful road construction. The approach used is highly correlated with the common knowledge of baking layer cakes in Malaysia. Students should be able to relate the procedure of baking a layer cake to the importance of following the correct methods of road construction. An understanding of basic statistics is necessary before starting this lesson. This lesson will take almost 60 minutes to complete. During activity breaks, students are required to answer questions and complete assigned tasks related to the subject.

Join me for a hands-on ride through the fundamentals of electronics and acoustics and the process of loudspeaker design and construction. We will learn about the engineering and art involved throughout music/movie recording and playback, the design and application of everything from microphones to DACs, amplifiers, and speakers. With the aid of computer assisted audio measuring equipment at the MIT Edgerton Center, we will analyze the frequency response and distortion of speaker drivers, and understand their effect on what we hear. Then we design our own speakersÄdriver selection, crossover networks, and enclosure designÄand build them in class!

This learning video continues the theme of an early BLOSSOMS lesson, Flaws of Averages, using new examples—including how all the children from Lake Wobegon can be above average, as well as the Friendship Paradox. As mentioned in the original module, averages are often worthwhile representations of a set of data by a single descriptive number. The objective of this module, once again, is to simply point out a few pitfalls that could arise if one is not attentive to details when calculating and interpreting averages. Most students at any level in high school can understand the concept of the flaws of averages presented here. The essential prerequisite knowledge for this video lesson is the ability to calculate an average from a set of numbers. Materials needed include: pen and paper for the students; a blackboard or equivalent; and coins (one per student) or something similar that students can repeatedly use to create a random event with equal chances of the two outcomes (e.g. flipping a fair coin). The coins or something similar are recommended for one of the classroom activities, which will demonstrate the idea of regression toward the mean. Another activity will have the students create groups to show how the average number of friends of friends is greater than or equal to the average number of friends in a group, which is known as The Friendship Paradox. The lesson is designed for a typical 50-minute class session.

This course focuses on works that caught the popular imagination in the past or present. It emphasizes texts that are related by genre, theme or style. The books studied in this course vary from semester to semester, and the topic for Fall 2006 is Detective Fictions.